Well I would have to say: not really. Most items that you might need, especially based on weather changes, you can really pick up. I would again say that the proper shoes and quality rain gear are the items you might have a hard time finding in some areas. Also if you happen to be larger (for example: shoe size, bra size or taller) then the population of the country you are visiting, you might have trouble with sizes. Quite honestly I was afraid of losing my bra or my bathing suit due to the fact that in so many of the areas I visited, I would not have been able to get my size.